Article
Genetic association study of polymorphisms in the catalase gene with the risk of osteonecrosis of the femoral head in the Korean population.
Osteoarthritis and cartilage - 1 Sept 2008
Kim T-H, Hong J M, Oh B, Cho Y S, Lee J-Y, Kim H-L, Shin E-S, Lee J-E, Park E K, Kim S-Y
Abstract excerpt
OBJECTIVE: Osteonecrosis (ON) of the femoral head frequently leads to progressive collapse of the femoral head followed by degenerative arthritis of the hip joint. Oxidative stress, which has been implicated in many pathological conditions, including vascular injury, recently has been suggested to play a part in the development of ON. Catalase (CAT) is a major antioxidant enzyme and a number of polymorphisms in...
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