Article
Single-nucleotide polymorphisms in the promoter of the CDK5 gene and lung cancer risk in a Korean population.
Journal of human genetics - 1 May 2009
Choi Hyo Seon, Lee Youngin, Park Kyong Hwa, Sung Jae Sook, Lee Jong-Eun, Shin Eun-Soon, Ryu Jeong-Seon, Kim Yeul Hong
Abstract excerpt
Cyclin-dependent kinase 5 (CDK5), a proline-directed serine/threonine kinase, which was originally known for its regulatory role in neuronal activities, has recently been suggested to play a role in extraneuronal activities. For example, a recent study detected overexpression of the CDK5 gene in non-small-cell lung cancer. Therefore, in order to explore the association of the CDK5 gene with lung cancer risk in a...
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