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Article

Associations among Insulin, Estrogen, and Fat Mass Gain over the Pubertal Transition in African-American and European-American Girls

18 Mar 2008

Abstract excerpt

CONTEXT: Age at menarche (AgeM) is earlier in African-American (AA) than in European-American (EA) girls. Neither the physiological cause nor the health implications of this difference are known. OBJECTIVE: We tested the hypotheses that higher insulin among AA vs. EA precipitates an earlier elevation of estradiol (E2), an associated earlier AgeM, and greater gain in body fat. SETTING: The study was conducted at a...

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PMID: 18349063
DOI: 10.1210/jc.2007-2776

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