Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Ontogeny of Distinct Reproductive Phenotypes in Girls at Risk for PCOS During the Postmenarchal Transition.

The Journal of clinical endocrinology and metabolism - 21 Jan 2026

Torchen Laura C, Aekka Apoorva, Brewer Kelly, Sisk Ryan, Ratnam Sarayu, Vendrami Camila, Miller Frank H, Dunaif Andrea

Abstract excerpt

CONTEXT: Daughters of women with polycystic ovary syndrome (PCOS-d) and girls with overweight/obesity (OW-g) have hyperandrogenemia (HA) beginning in childhood. However, other features of their early reproductive phenotypes differ, suggesting that there are distinct mechanisms conferring increased risk for PCOS. OBJECTIVE: We performed a cross-sectional study of adolescent girls during the early postmenarchal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Follicle Stimulating Hormone
Share to Hyperandrogenism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Luteinizing Hormone

Share to Menarche

Share to Overweight

Share to Polycystic Ovary Syndrome

Share to Sex Hormone-Binding Globulin

Share to Testosterone

Source

Open in PubMed Open full text

Identifiers

PMID: 40578837
DOI: 10.1210/clinem/dgaf363
PMCID: PMC12571120

Genes

SHBG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Ontogeny of Distinct Reproductive Phenotypes in Girls at Risk for PCOS During the Postmenarchal Transition.PMID 40578837Read ↗

Shared Pathophysiological Mechanisms and Genetic Factors in Early Menarche and Polycystic Ovary SyndromeSemantic proximity Read ↗

History of Polycystic Ovary Syndrome, Premature Adrenarche, and Hyperandrogenism in Pediatric EndocrinologySemantic proximity Read ↗

Developmental Origin of Reproductive and Metabolic Dysfunctions: Androgenic Versus Estrogenic ReprogrammingSemantic proximity Read ↗

High Prevalence of Adolescents “At Risk for PCOS” and Links to Genetic Susceptibility to PCOSSemantic proximity Read ↗

Early programming of reproductive health and fertility: novel neuroendocrine mechanisms and implications in reproductive medicineSemantic proximity Read ↗

Clinical and Biochemical Characteristics of Girls With Polycystic Ovary Syndrome Presenting With Amenorrhea.Semantic proximity Read ↗

Adolescent girls with polycystic ovary syndrome showing different phenotypes have a different metabolic profile associated with increasing androgen levelsSemantic proximity Read ↗

Adolescent polycystic ovary syndrome.Semantic proximity Read ↗

Pathogenesis of polycystic ovary syndrome: multifactorial assessment from the foetal stage to menopause.Semantic proximity Read ↗

Polycystic Ovary Syndrome in AdolescenceSemantic proximity Read ↗

Update in Hyper- and Hypogonadotropic AmenorrheaSemantic proximity Read ↗

Phenotypic Characterization of Polycystic Ovary Syndrome in Adolescents Based on Menstrual Irregularity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.