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Article

CYP19A1 promoter methylation in saliva associated with milestones of pubertal timing in urban girls

20 Mar 2014

Abstract excerpt

BACKGROUND: Childhood obesity and early puberty are intermediate risk factors for later metabolic and reproductive disorders including diabetes, polycystic ovarian syndrome (PCOS), and breast cancer. Atypical methylation patterns in genes related to hormone and adipose metabolism, such as CYP19A1 (aromatase) and PPARG (peroxisome proliferator-activated receptor gamma), are associated with alterations in gene...

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Share to Epigenetics and DNA Methylation
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PMID: 24649863
DOI: 10.1186/1471-2431-14-78

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