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Article

Alleles of afd1 dissect REC8 functions during meiotic prophase I.

Journal of cell science - 15 Aug 2006

Golubovskaya Inna N, Hamant Olivier, Timofejeva Ljuda, Wang Chung-Ju Rachel, Braun David, Meeley Robert, Cande W Zacheus

Abstract excerpt

REC8 is a master regulator of chromatin structure and function during meiosis. Here, we dissected the functions of absence of first division (afd1), a maize rec8/alpha-kleisin homolog, using a unique afd1 allelic series. The first observable defect in afd1 mutants is the inability to make a leptotene chromosome. AFD1 protein is required for elongation of axial elements but not for their initial recruitment, thus...

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Source

Identifiers

PMID: 16868028
DOI: 10.1242/jcs.03054

Genes

REC8
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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