Development of Saccharomyces cerevisiae accumulating excessive amount of glycogen and its effects on gut microbiota in a mouse model.

doi:10.1016/j.ijbiomac.2024.137589

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Article

Development of Saccharomyces cerevisiae accumulating excessive amount of glycogen and its effects on gut microbiota in a mouse model.

International journal of biological macromolecules - 1 Dec 2024

Ban So Young, Yun Da-Young, Yum Su-Jin, Jeong Hee-Gon, Park Jong-Tae

Abstract excerpt

Saccharomyces cerevisiae accumulates glycogen, a hyperbranched glucose polymer with multiple bio-functionalities. In this study, mutants of S. cerevisiae that accumulate excessive amounts of glycogen were developed through UV mutagenesis. From over 30,000 mutants, the mutant strain CEY1, which exhibited the highest glycogen production, was selected using iodine vapor screening. The glycogen structures of wild...

Topics

Glycogen
Saccharomyces cerevisiae
Animals
Gastrointestinal Microbiome
Mice
Fermentation
Mutation

Source

Open in PubMed

Identifiers

PMID: 39557260
DOI: 10.1016/j.ijbiomac.2024.137589

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