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Article

Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract.

PLoS biology - 1 Oct 2023

Connor Christopher H, Zucoloto Amanda Z, Munnoch John T, Yu Ian-Ling, Corander Jukka, Hoskisson Paul A, McDonald Braedon, McNally Alan

Abstract excerpt

Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections outside of the intestine and are a major causative agent of urinary tract infections. Treatment of these infections is increasingly frustrated by antimicrobial resistance (AMR) diminishing the number of effective therapies available to clinicians. Incidence of multidrug resistance (MDR) is not uniform across the phylogenetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37847672
DOI: 10.1371/journal.pbio.3002329
PMCID: PMC10581457

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