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Article

Immunoexpression of tumor suppressor genes p53, p21 WAF1/CIP1 and p27 KIP1 in humam astrocystic tumors.

Arquivos de neuro-psiquiatria - 1 Dec 2007

Faria Mário Henrique Girão, Patrocínio Régia Maria do Socorro Vidal do, Moraes Filho Manoel Odorico de, Rabenhorst Silvia Helena Barem

Abstract excerpt

The aim of the present study was to evaluate the tumor suppressor genes p53, p21 WAF1/CIP1 and p27 KIP1 expression in astrocytic tumors, correlating the findings with the histopathological grade (WHO). An immunohistochemical study of the p53, p21 and p27 proteins using the streptavidin-biotin-peroxidase method was performed in fifty-five astrocytomas (13 grade I, 14 grade II, 7 grade III and 21 grade IV) and five...

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PMID: 18345413
DOI: 10.1590/s0004-282x2007000700004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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