Article
Synergistic role of Igf2 and Dlk1 in fetal liver development and hematopoiesis in bi-maternal mice.
The Journal of reproduction and development - 1 Jun 2008
Wu Qiong, Kawahara Manabu, Kono Tomohiro
Abstract excerpt
Mouse bi-maternal embryos (BMEs) that contain two haploid sets of genomes from non-growing (ng) and fully-grown (fg) oocytes develop to embryonic day (E) 13.5. However, the ng/fg BMEs never develop beyond E13.5 because of repression of the paternally expressed imprinted genes, Igf2 and Dlk1. The present study was conducted to address the issue of whether fetal hematopoietic disorder is involved in the restricted...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
