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Article

Association of the dusp6 (mkp3) gene with mouse brain weight and forebrain structure.

Journal of child neurology - 1 Jun 2008

Liu Bin

Abstract excerpt

PYST1/MKP3 is a negative feedback modulator of fibroblast growth factor 8 (Fgf8) signaling in the mammalian isthmic organizer of the brain, which affects the development of the midbrain and the hindbrain. The Dusp6 (Mkp3) gene is also highly expressed in the mouse embryonic forebrain. However, its role in forebrain development and function remains largely unknown. In this study, association analyses were...

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Identifiers

PMID: 18344456
DOI: 10.1177/0883073807313042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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