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Article

IL-4-induced Stat6 activities affect apoptosis and gene expression in breast cancer cells.

Cytokine - 1 Apr 2008

Zhang Wen Jie, Li Ben Hui, Yang Xian Zi, Li Pin Dong, Yuan Qin, Liu Xiao Hong, Xu Shuang Bing, Zhang Yan, Yuan Jia, Gerhard Glenn S, Masker Kathryn K, Dong Cheng, Koltun Walter A, Chorney Michael J

Abstract excerpt

IL-4-induced Stat6 signaling is active in a variety of cell types, including immune cells and cancer cells, and plays an important role in the regulation of gene expression. Using EMSA gel shift assay and an antibody to Stat6, we phenotyped two breast cancer cell lines, ZR-75-1 being active Stat6(high) phenotype and BT-20 being defective Stat6(null) phenotype, respectively. Breast cancer cells carrying...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18342537
DOI: 10.1016/j.cyto.2008.01.016

Genes

CCL26
CISH
DUSP1
EGLN3
FOS
FOSB
SIDT1
SOCS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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