Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PC3 Human Prostate Carcinoma Cell Holoclones Contain Self-renewing Tumor-Initiating Cells

13 Mar 2008

Abstract excerpt

Primary keratinocytes exhibit three typical clonal morphologies represented by holoclones, meroclones, and paraclones, with holoclones containing self-renewing stem cells, and meroclones and paraclones containing more mature and differentiated cells. Interestingly, long-term-cultured human epithelial cancer cells in clonal cultures also form holoclones, meroclones, and paraclones, and tumor cell holoclones have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cellular Mechanics and Interactions
Share to Hippo pathway signaling and YAP/TAZ

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18339862
DOI: 10.1158/0008-5472.can-07-5878

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PC3 Human Prostate Carcinoma Cell Holoclones Contain Self-renewing Tumor-Initiating CellsPMID 18339862Read ↗

Patient-derived prostate cancer organoids require α6-integrins for self-renewal and recapitulate genetic heterogeneity and histopathology of the original tumorsSemantic proximity Read ↗

In vitro propagation and characterization of neoplastic stem/progenitor‐like cells from human prostate cancer tissueSemantic proximity Read ↗

PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesisSemantic proximity Read ↗

Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivoSemantic proximity Read ↗

Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells.Semantic proximity Read ↗

Prostate cancer stem/progenitor cells: Identification, characterization, and implicationsSemantic proximity Read ↗

Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived OrganoidsSemantic proximity Read ↗

Single luminal epithelial progenitors can generate prostate organoids in culture.Semantic proximity Read ↗

Telomerase-immortalized non-malignant human prostate epithelial cells retain the properties of multipotent stem cells.Semantic proximity Read ↗

Arsenic-Transformed Malignant Prostate Epithelia Can Convert Noncontiguous Normal Stem Cells into an Oncogenic PhenotypeSemantic proximity Read ↗

Primary cell cultures as models of prostate cancer developmentSemantic proximity Read ↗

Differentiation of prostate epithelial cell cultures by matrigel/ stromal cell glandular reconstruction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.