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Article

Phosphorylation in the Charged Linker Modulates Interactions and Secretion of Hsp90β.

Cells - 5 Jul 2021

Weidenauer Lorenz, Quadroni Manfredo

Abstract excerpt

Hsp90β is a major chaperone involved in numerous cellular processes. Hundreds of client proteins depend on Hsp90β for proper folding and/or activity. Regulation of Hsp90β is critical to coordinate its tasks and is mediated by several post-translational modifications. Here, we focus on two phosphorylation sites located in the charged linker region of human Hsp90β, Ser226 and Ser255, which have been frequently...

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Identifiers

PMID: 34359868
DOI: 10.3390/cells10071701
PMCID: PMC8304327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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