Article
Stromal cell-derived factor-1 promotes bone marrow-derived cells differentiation to cardiomyocyte phenotypes in vitro.
Cell proliferation - 1 Apr 2008
Chen M, Xie H-Q, Deng L, Li X-Q, Wang Y, Zhi W, Yang Z-M
Abstract excerpt
OBJECTIVE: Recent studies have demonstrated the potential of bone marrow-derived cells (BMDC) to differentiate into cardiomyocytes. Up-regulation of stromal cell-derived factor-1 (SDF-1), a member of the chemokine CXC subfamily, mediating recruitment of BMDC has been documented in infarcted myocardium; however, it remains unknown whether SDF-1 plays a role in cardiomyogenesis of BMDC. MATERIALS AND METHODS:...
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