Article
Buccal swabs and treated cards: methodological considerations for molecular epidemiologic studies examining pediatric populations.
American journal of epidemiology - 15 May 2008
Beckett Sara M, Laughton Stephen J, Pozza Luciano Dalla, McCowage Geoffrey B, Marshall Glenn, Cohn Richard J, Milne Elizabeth, Ashton Lesley J
Abstract excerpt
Self-collection of buccal cells provides a noninvasive method for obtaining biologic samples for genetic analyses in pediatric studies. Nevertheless, low yields, microbial contamination, and degradation of buccal samples present challenges for epidemiologic studies incorporating genetic investigations. The aims of this study were to compare the quality and yield of DNA extracted from buccal specimens with...
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