Article
Quality assessment of buccal versus blood genomic DNA using the Affymetrix 500 K GeneChip.
BMC genetics - 8 Nov 2007
Woo Jessica G, Sun Guangyun, Haverbusch Mary, Indugula Subbarao, Martin Lisa J, Broderick Joseph P, Deka Ranjan, Woo Daniel
Abstract excerpt
BACKGROUND: With the advent of genome-wide genotyping, the utility of stored buccal brushes for DNA extraction and genotyping has been questioned. We sought to describe the genomic DNA yield and concordance between stored buccal brushes and blood samples from the same individuals in the context of Affymetrix 500 K Human GeneChip genotyping. RESULTS: Buccal cytobrushes stored for approximately 7 years at -80...
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