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Article

Interleukin-5 receptor subunit oligomerization and rearrangement revealed by fluorescence resonance energy transfer imaging.

The Journal of biological chemistry - 9 May 2008

Zaks-Zilberman Meirav, Harrington Adrian E, Ishino Tetsuya, Chaiken Irwin M

Abstract excerpt

Interleukin (IL)-5 exerts hematopoietic functions through binding to the IL-5 receptor subunits, alpha and betac. Specific assembly steps of full-length subunits as they occur in cell membranes, ultimately leading to receptor activation, are not well understood. We tracked the oligomerization of IL-5 receptor subunits using fluorescence resonance energy transfer (FRET) imaging. Full-length IL-5Ralpha and betac...

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Identifiers

PMID: 18326494
DOI: 10.1074/jbc.M710230200
PMCID: PMC2442328

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CFP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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