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Article

The involvement of HIV-1 RNAse H in resistance to nucleoside analogues.

The Journal of antimicrobial chemotherapy - 1 May 2008

Roquebert Bénédicte, Marcelin Anne-Geneviève

Abstract excerpt

Some recent studies have underlined the role of the entire reverse transcriptase (RT) and in particular its carboxy-terminal domain from amino acid 427 to amino acid 560 [the ribonuclease H (RNAse H) domain] in resistance to nucleoside RT inhibitors (NRTIs). RNAse H is implicated in catalysing th...

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PMID: 18325896
DOI: 10.1093/jac/dkn060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18325896-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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