Article
Mechanisms of HIV-1 nucleoside reverse transcriptase inhibitor resistance: is it all figured out?
Current opinion in investigational drugs (London, England : 2000) - 1 Mar 2001
Naeger L K, Miller M D
Abstract excerpt
The mechanistic basis for some examples of HIV-1 NRTI-resistance can be examined using altered incorporation of nucleoside analogs and surveying what is known about the more recently described mechanisms of chain-terminator removal. The complexity of these resistance mechanisms and the interplay...
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