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Article

Mechanisms of HIV-1 nucleoside reverse transcriptase inhibitor resistance: is it all figured out?

Current opinion in investigational drugs (London, England : 2000) - 1 Mar 2001

Naeger L K, Miller M D

Abstract excerpt

The mechanistic basis for some examples of HIV-1 NRTI-resistance can be examined using altered incorporation of nucleoside analogs and surveying what is known about the more recently described mechanisms of chain-terminator removal. The complexity of these resistance mechanisms and the interplay with other factors that contribute to NRT1 resistance are only just beginning to be appreciated.

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PMID: 11575701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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