Article
Regulatory polymorphisms in the promoter of CXCL10 gene and disease progression in male hepatitis B virus carriers.
Gastroenterology - 1 Mar 2008
Deng Guohong, Zhou Gangqiao, Zhang Rong, Zhai Yun, Zhao Wenli, Yan Zehui, Deng Chunqing, Yuan Xiaoyan, Xu Baoyan, Dong Xiaojia, Zhang Xiumei, Zhang Xuqing, Yao Zhijian, Shen Yan, Qiang Boqing, Wang Yuming, He Fuchu
Abstract excerpt
BACKGROUND & AIMS: The importance of expression of interferon gamma-inducible protein of 10 kilodaltons (IP-10, CXCL10) during chronic hepatitis B virus (HBV) infection has been recently emphasized. In this report, we investigated whether the naturally occurred sequence variations in the CXCL10 gene impact liver damage and disease progression of chronic HBV infection. METHODS: A hospital-based case-control study...
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