Article
Influence of interleukin-10 gene promoter polymorphisms on disease progression in patients chronically infected with hepatitis B virus.
The American journal of gastroenterology - 1 Aug 2002
Miyazoe Seiji, Hamasaki Keisuke, Nakata Keisuke, Kajiya Yuji, Kitajima Kayo, Nakao Kazuhiko, Daikoku Manabu, Yatsuhashi Hiroshi, Koga Michiaki, Yano Michitami, Eguchi Katsumi
Abstract excerpt
OBJECTIVES: The role of host genetic factors in chronic hepatitis B virus (HBV) infection is not fully understood. We studied the influence of tumor necrosis factor-alpha (TNF-alpha) and interleukin-10 (IL-10) gene promoter polymorphisms on disease progression in HBV carriers. METHODS: The sample population included 213 Japanese HBV carriers and 52 healthy volunteers. Of 213 HBV carriers, 66 were considered to be...
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