Article
High rate of mobilization for blaCTX-Ms.
Emerging infectious diseases - 1 Mar 2008
Barlow Miriam, Reik Rebecca A, Jacobs Stephen D, Medina Mónica, Meyer Matthew P, McGowan John E, Tenover Fred C
Abstract excerpt
We constructed a phylogenetic analysis of class A beta-lactamases and found that the blaCTX-Ms have been mobilized to plasmids approximately 10 times more frequently than other class A beta-lactamases. We also found that the blaCTX-Ms are descended from a common ancestor that was incorporated in ancient times into the chromosome of the ancestor of Kluyvera species through horizontal transfer. Considerable...
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