Beta-lactamases of Kluyvera ascorbata, probable progenitors of some plasmid-encoded CTX-M types.

doi:10.1128/AAC.46.9.3045-3049.2002

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Beta-lactamases of Kluyvera ascorbata, probable progenitors of some plasmid-encoded CTX-M types.

Antimicrobial agents and chemotherapy - 1 Sept 2002

Humeniuk Christel, Arlet Guillaume, Gautier Valerie, Grimont Patrick, Labia Roger, Philippon Alain

Abstract excerpt

Kluyvera ascorbata produces a beta-lactamase that results in an atypical susceptibility pattern, including low-level resistance to penicillins, cephalothin, and cefuroxime, but this resistance is reversed by clavulanate. Ten nucleotide sequences of the corresponding gene, bla(KLUA), were obtained and were found to have minor variations (96 to 100%). Otherwise, bla(KLUA) was found to be similar (95 to 100%) to...

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Beta-lactamases of Kluyvera ascorbata, probable progenitors of some plasmid-encoded CTX-M types.

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