Article
CTX-M-type β-lactamases: a successful story of antibiotic resistance.
International journal of medical microbiology : IJMM - 1 Aug 2013
D'Andrea Marco Maria, Arena Fabio, Pallecchi Lucia, Rossolini Gian Maria
Abstract excerpt
Production of extended-spectrum β-lactamases (ESBLs) is the principal mechanism of resistance to oxyimino-cephalosporins evolved by members of the family Enterobacteriaceae. Among the several ESBLs emerged among clinical pathogens, the CTX-M-type enzymes have proved the most successful in terms of promiscuity and diffusion in different epidemiological settings, where they have largely replaced and outnumbered...
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