Article
Implications of mismatch repair genes hMLH1 and hMSH2 in patients with sporadic renal cell carcinoma.
BJU international - 1 Aug 2008
Rubio-Del-Campo Antonio, Salinas-Sánchez Antonio S, Sánchez-Sánchez Francisco, Giménez-Bachs José M, Donate-Moreno María J, Pastor-Navarro Héctor, Carrión-López Pedro, Escribano Julio
Abstract excerpt
OBJECTIVES: To analyse the implications of DNA mismatch repair genes hMLH1 and hMSH2 in sporadic renal cell carcinoma (RCC). MATERIALS AND METHODS: Specimens of tumour and healthy renal tissue were collected from 89 patients treated for sporadic RCC. Another 95 blood samples taken from individuals with no history of cancer were also analysed. After DNA extraction and PCR amplification, microsatellite instability...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
