Article
No association between an allele at the D2 dopamine receptor gene (DRD2) and alcoholism.
JAMA - 2 Oct 1991
Gelernter J, O'Malley S, Risch N, Kranzler H R, Krystal J, Merikangas K, Kennedy J L, Kidd K K
Abstract excerpt
OBJECTIVE: --We attempted to replicate a positive allelic association between the A1 allele of DRD2 (the D2 dopamine receptor locus) and alcoholism that has been reported. DESIGN: --We compared allele frequencies at the previously described Taq I restriction fragment length polymorphism system of DRD2 in alcoholics and random population controls. SUBJECTS: --The alcoholic subjects were 44 unrelated white...
Topics
- Adult
- Alcoholism
- Alleles
- DNA
- Female
- Humans
- Male
- Middle Aged
- Receptors, Dopamine
- Receptors, Dopamine D2