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Article

Evidence of QTL on 15q21 for high-density lipoprotein cholesterol: the National Heart, Lung, and Blood Institute Family Heart Study (NHLBI FHS).

Atherosclerosis - 1 Jan 2007

Feitosa Mary F, Province Michael A, Heiss Gerardo, Arnett Donna K, Myers Richard H, Pankow James S, Hopkins Paul N, Borecki Ingrid B

Abstract excerpt

A genome-wide linkage scan was conducted to identify regions potentially having quantitative trait loci (QTLs) influencing high-density lipoprotein (HDL) cholesterol. We found suggestive evidence of a QTL (lod score (LOD)=1.75, p=0.00224, and q=0.07649) influencing the variation of plasma levels of age- and sex-adjusted HDL-cholesterol on chromosome 15q21 at marker D15S659 in the NHLBI FHS data. Owing to the...

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PMID: 16529751
DOI: 10.1016/j.atherosclerosis.2006.02.006

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