HIV and human leukocyte antigen association--the Indian scenario.

Abstract excerpt

Genetic factors such as human leukocyte antigen (HLA) affect the infection and progression of HIV disease. The dependence of effective cytotoxic T lymphocyte (CTL) activity on HIV-specific T-helper responses has become increasingly evident and studies provide strong evidence that T-helper responses and the magnitude of CTL responses are closely linked. HLA haplotype A11-B35-Cw4 has been associated with rapid...

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