Article
Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach.
PLoS medicine - 4 Mar 2008
Chen Lina, Smith George Davey, Harbord Roger M, Lewis Sarah J
Abstract excerpt
BACKGROUND: Alcohol has been reported to be a common and modifiable risk factor for hypertension. However, observational studies are subject to confounding by other behavioural and sociodemographic factors, while clinical trials are difficult to implement and have limited follow-up time. Mendelian randomization can provide robust evidence on the nature of this association by use of a common polymorphism in...
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