Article
Cloning of a novel cell type from human fetal liver expressing cytoplasmic CD3 delta and epsilon but not membrane CD3.
International immunology - 1 Apr 1991
Hori T, de Waal Malefyt R, Duncan B W, Harrison M R, Roncarolo M G, Spits H
Abstract excerpt
Seventeen-week human fetal liver cells cultured with a feeder cell mixture of irradiated PBL, irradiated JY cells (an EBV-transformed B cell line) and PHA contained a subpopulation of CD3- cells in addition to a major population of T cells with the mature phenotype. After 12 days in culture, CD3-...
Topics
- Antigens, Differentiation, T-Lymphocyte
- CD3 Complex
- Cell Membrane
- Clone Cells
- Cytoplasm
- Fetus
- Gene Rearrangement, T-Lymphocyte
- Hematopoietic Stem Cells
- Humans
- Killer Cells, Natural
- Liver
- Phenotype
- Receptors, Antigen, T-Cell
- T-Lymphocytes