Article
Evaluating the association of common PBX1 variants with type 2 diabetes.
BMC medical genetics - 29 Feb 2008
Duesing Konsta, Charpentier Guillaume, Marre Michel, Tichet Jean, Hercberg Serge, Balkau Beverley, Froguel Philippe, Gibson Fernando
Abstract excerpt
BACKGROUND: PBX1 is a biological candidate gene for type 2 diabetes at the 1q21-q24 susceptibility locus. The aim of this study was to evaluate the association of common PBX1 variants with type 2 diabetes in French Caucasian subjects. METHODS: Employing a case-control design, we genotyped 39 SNPs spanning the PBX1 locus in 3,093 subjects to test for association with type 2 diabetes. RESULTS: Several PBX1 SNPs,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
