Article
PSMD9 gene variants within NIDDM2 may rarely contribute to type 2 diabetes.
Journal of cellular physiology - 1 Sept 2007
Gragnoli C, Cronsell J
Abstract excerpt
Multiple genome-wide scans in different populations have linked the chromosome 12q24 region, known as NIDDM2 (non-insulin-dependent-diabetes, locus 2), to type 2 diabetes. Within NIDDM2 we examined the PSMD9 (proteasome modulator 9/Bridge-1) gene that encodes a PDZ-domain transcriptional coactivator of insulin production. Our goal was to identify a potential contribution of the PSMD9 gene to type 2 diabetes in...
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