Bradycardia in Athletes: Prevalence, Mechanisms, and Risks.

doi:10.1161/CIRCULATIONAHA.125.076170

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Article

Bradycardia in Athletes: Prevalence, Mechanisms, and Risks.

Circulation - 3 Mar 2026

D'Ambrosio Paolo, De Paepe Jarne, Spencer Luke W, Ohanian Monique, Janssens Kristel, Mitchell Amy M, Flannery M Darragh, Bekhuis Youri, Pauwels Rik, Delpire Boris, Dausin Christophe, Rowe Stephanie J, Van Puyvelde Tim, Young Paul E, Soka Magdalena J, Johnson Renee, Yu Chenglong, Morris Gwilym M, Robyns Tomas, Lacaze Paul, Giannoulatou Eleni, Kistler Peter M, Kalman Jonathan M, Heidbuchel Hein, Willems Rik, Claessen Guido, Fatkin Diane, La Gerche André

Abstract excerpt

BACKGROUND: Sinus bradycardia is a well-recognized physiological adaptation in endurance athletes, primarily attributed to sinus node remodeling or increased vagal modulation. Although genetic influences on resting heart rate (HR) have been observed, the genetic contribution to athletic bradycardia has not been elucidated. METHODS: We phenotyped current and former elite endurance athletes in the Pro@Heart cohort...

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PMID: 41410046
DOI: 10.1161/CIRCULATIONAHA.125.076170
PMCID: PMC12952486

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