Cholesterol 7alpha-hydrolase (CYP7A1) c.-278A>C promoter polymorphism in gallstone disease patients.

doi:10.1089/gte.2007.0067

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Cholesterol 7alpha-hydrolase (CYP7A1) c.-278A>C promoter polymorphism in gallstone disease patients.

Genetic testing - 1 Mar 2008

Juzyszyn Zygmunt, Kurzawski Mateusz, Lener Agnieszka, Modrzejewski Andrzej, Pawlik Andrzej, Droździk Marek

Abstract excerpt

There is growing evidence that gallstone formation may be genetically determined. Cholesterol 7alpha-hydrolase (CYP7A1) is an enzyme that catalyzes the first, rate-limiting reaction of cholesterol catabolic pathway. Recently, a common c.-278A>C polymorphism (rs3808607:G>T) has been described in CYP7A1 gene, associated with altered plasma lipid levels. The aim of this study was to verify the finding that CYP7A1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Cholesterol 7-alpha-Hydroxylase

Share to Gallstones

Share to Gene Frequency

Share to Poland

Share to Polymorphism, Restriction Fragment Length

Share to Promoter Regions, Genetic

Source

Open in PubMed

Identifiers

PMID: 18307386
DOI: 10.1089/gte.2007.0067

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cholesterol 7alpha-hydrolase (CYP7A1) c.-278A>C promoter polymorphism in gallstone disease patients.PMID 18307386Read ↗

CYP7A1 (-204 A>C; rs3808607 and -469 T>C; rs3824260) promoter polymorphisms and risk of gallbladder cancer in North Indian population.Semantic proximity Read ↗

Role of genetic variant A-204C of cholesterol 7alpha-hydroxylase (CYP7A1) in susceptibility to gallbladder cancer.Semantic proximity Read ↗

Implication of genetic variation at the promoter and exon1 of UGT1A1 in occurrence of cholelithiasis in Tunisia.Semantic proximity Read ↗

Gilbert syndrome as a predisposing factor for cholelithiasis risk in the Greek adult population.Semantic proximity Read ↗

Association of APOE-C1 gene cluster polymorphisms with gallstone disease.Semantic proximity Read ↗

Common polymorphisms in the CYP7A1 gene do not contribute to variation in rates of bile acid synthesis and plasma LDL cholesterol concentration.Semantic proximity Read ↗

Modulating effect of the A-278C promoter polymorphism in the cholesterol 7alpha-hydroxylase gene on serum lipid levels in normolipidaemic and hypertriglyceridaemic individuals.Semantic proximity Read ↗

Polymorphisms at cholesterol 7alpha-hydroxylase, apolipoproteins B and E and low density lipoprotein receptor genes in patients with gallbladder stone disease.Semantic proximity Read ↗

Genetics of gallstone disease.Semantic proximity Read ↗

Relationship between CYP7A1 -204A>C polymorphism with gallbladder stone disease and serum lipid levels: a meta-analysis.Semantic proximity Read ↗

ApoB-100, ApoE and CYP7A1 gene polymorphisms in Mexican patients with cholesterol gallstone disease.Semantic proximity Read ↗

Hepatic cholesterol transporter ABCG8 polymorphisms in gallstone disease in an Indian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.