Colocalization of lymphocytes bearing gamma delta T-cell receptor and heat shock protein hsp65+ oligodendrocytes in multiple sclerosis.

Abstract excerpt

The presence of T lymphocytes bearing the gamma delta T-cell receptor (TCR gamma delta) has been studied immunocyto-chemically in central nervous system (CNS) tissue from 13 patients with multiple sclerosis (MS), 4 with inflammatory non-MS CNS disorders, 6 with other neurological diseases, and 3 with nonneurologic conditions. Twenty-eight of 43 MS lesions contained TCR gamma delta cells and these were most...

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