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Article

Regulation of Chondrocytic Gene Expression by Biomechanical Signals

1 Jan 2008

Abstract excerpt

Cartilage is a mechanosensitive tissue, which means that it can perceive and respond to biomechanical signals. Despite the known importance of biomechanical signals in the etiopathogenesis of arthritic diseases and their effectiveness in joint restoration, little is understood about their actions at the cellular level. Recent molecular approaches have revealed that specific biomechanical stimuli and cell...

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PMID: 18304028
DOI: 10.1615/critreveukargeneexpr.v18.i2.30

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