Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of TIMP-4 gene polymorphism with the risk of osteoarthritis in the Korean population.

Rheumatology international - 1 Jul 2008

Lee H J, Lee G H, Nah S, Lee K H, Yang H, Kim Y M, Chun W, Hong S, Kim S

Abstract excerpt

Due to an imbalance in the MMP:TIMP ratio determined a tissue damage in arthritis, it is hypothesized that polymorphic variations of the TIMP genes are associated with regulation of the MMP:TIMP balance. To test this hypothesis, the presence of single nucleotide polymorphisms (SNPs) located in the human TIMP-2 and TIMP-4 genes was confirmed in the Korean RA and OA patients. We performed a case-control study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Aged
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Osteoarthritis

Share to Tissue Inhibitor of Metalloproteinase-2

Share to Tissue Inhibitor of Metalloproteinases

Source

Identifiers

PMID: 18301898
DOI: 10.1007/s00296-008-0545-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of TIMP-4 gene polymorphism with the risk of osteoarthritis in the Korean population.PMID 18301898Read ↗

TIMP-2 SNPs rs7342880 and rs4789936 are linked to risk of knee osteoarthritis in the Chinese Han Population.Semantic proximity Read ↗

Association of ADAMTS-5 gene polymorphisms with the susceptibility to knee osteoarthritis in a Chinese Han populationSemantic proximity Read ↗

Association betweenMMP3andTIMP3polymorphisms and risk of osteoarthritisSemantic proximity Read ↗

Association of ADAMTS-5 gene polymorphisms with the susceptibility to knee osteoarthritis in a Chinese Han population.Semantic proximity Read ↗

ADAMTS14 gene polymorphism associated with knee osteoarthritis in Thai women.Semantic proximity Read ↗

The association between MMP-1 gene rs1799750 polymorphism and knee osteoarthritis risk.Semantic proximity Read ↗

Association of TIMP-2 Rs8179090 Genotypes With Lung Cancer Risk in Taiwan.Semantic proximity Read ↗

Association between transforming growth factor-beta1 T869C polymorphism and rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

Association between transforming growth factor-beta 1 gene single nucleotide polymorphisms and knee osteoarthritis susceptibility in a Chinese Han population.Semantic proximity Read ↗

Tissue Inhibitor of Metalloproteinases-4. The road less traveledSemantic proximity Read ↗

Association of CTLA4 gene A-G polymorphism with rheumatoid arthritis in Chinese.Semantic proximity Read ↗

Genetic polymorphism of the tissue inhibitor of metalloproteinase-1 is associated with an increased risk of endometrial cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.