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Article

SOD1 and amyotrophic lateral sclerosis: mutations and oligomerization.

PloS one - 27 Feb 2008

Banci Lucia, Bertini Ivano, Boca Mirela, Girotto Stefania, Martinelli Manuele, Valentine Joan Selverstone, Vieru Miguela

Abstract excerpt

There are about 100 single point mutations of copper, zinc superoxide dismutase 1 (SOD1) which are reported (http://alsod.iop.kcl.ac.uk/Als/index.aspx) to be related to the familial form (fALS) of amyotrophic lateral sclerosis (ALS). These mutations are spread all over the protein. It is well documented that fALS produces protein aggregates in the motor neurons of fALS patients, which have been found to be...

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Share to Amyotrophic Lateral Sclerosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18301754
DOI: 10.1371/journal.pone.0001677
PMCID: PMC2250751

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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