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Article

Cu/Zn superoxide dismutase can form pore-like structures.

Biochemical and biophysical research communications - 26 Dec 2003

Chung Jinhyuk, Yang Hoichang, de Beus Mitchel D, Ryu Chang Y, Cho Kilwon, Colón Wilfredo

Abstract excerpt

Mutations in Cu/Zn superoxide dismutase (SOD) are associated with familial amyotrophic lateral sclerosis (FALS), a neurodegenerative disease that is characterized by the selective death of motor neurons. Despite the genetic association made between the protein and the disease, the mechanism by which the mutant SOD proteins become toxic is still a mystery. Using wild-type SOD and three pathogenic mutants (A4V,...

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Identifiers

PMID: 14651952
DOI: 10.1016/j.bbrc.2003.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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