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Association of ADAM family members with proliferation signaling and disease progression in multiple myeloma

11 Sept 2024

Abstract excerpt

Abstract Multiple myeloma (MM) is a hematological malignancy whose curability is greatly challenged by recurrent patient relapses and therapy resistance. We have previously proposed the high expression of ADAM8, ADAM9 and ADAM15 (A Disintegrin And Metalloproteinase 8/9/15) as adverse prognostic markers in MM. This study focused on the so far scarcely researched role of ADAM8/9/15 in MM using two patient cohorts...

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PMID: 39261477
DOI: 10.1038/s41408-024-01133-4

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