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Article

Impaired pressure-induced constriction in mouse middle cerebral arteries of ASIC2 knockout mice.

American journal of physiology. Heart and circulatory physiology - 1 Apr 2008

Gannon Kimberly P, Vanlandingham Lauren G, Jernigan Nikki L, Grifoni Samira C, Hamilton Gina, Drummond Heather A

Abstract excerpt

Recent studies from our laboratory demonstrated the importance of mechanosensitive epithelial Na(+) channel (ENaC) proteins in pressure-induced constriction in renal and cerebral arteries. ENaC proteins are closely related to acid-sensing ion channel 2 (ASIC2), a protein known to be required for normal mechanotransduction in certain sensory neurons. However, the role of the ASIC2 protein in pressure-induced...

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Share to Acid Sensing Ion Channels
Share to Epithelial Sodium Channels

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mechanotransduction, Cellular

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Source

Identifiers

PMID: 18296560
DOI: 10.1152/ajpheart.01380.2007

Genes

ASIC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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