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Article

Pressure-induced constriction is inhibited in a mouse model of reduced betaENaC.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Sept 2009

VanLandingham Lauren G, Gannon Kimberly P, Drummond Heather A

Abstract excerpt

Recent studies suggest certain epithelial Na(+) channel (ENaC) proteins may be components of mechanosensitive ion channel complexes in vascular smooth muscle cells that contribute to pressure-induced constriction in middle cerebral arteries (MCA). However, the role of a specific ENaC protein, betaENaC, in pressure-induced constriction of MCAs has not been determined. The goal of this study was to determine...

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Share to Epithelial Sodium Channels
Share to Mechanotransduction, Cellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Muscle, Smooth, Vascular

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Identifiers

PMID: 19553501
DOI: 10.1152/ajpregu.00212.2009
PMCID: PMC2739788

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