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Article

Contrasting vascular effects caused by loss of Bardet-Biedl syndrome genes.

American journal of physiology. Heart and circulatory physiology - 1 Dec 2010

Beyer Andreas M, Guo Deng-Fu, Sheffield Val C, Rahmouni Kamal

Abstract excerpt

Bardet-Biedl syndrome (BBS) is a genetically heterogeneous, autosomal-recessive disorder associated with several clinical features including obesity, hypertension, and cardiovascular abnormalities. BBS proteins play an important role in the function of cilia, a mechanosensory organelle in endothelial cells, but whether these proteins are directly involved in the regulation of vascular function is unclear. Here,...

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Identifiers

PMID: 20852044
DOI: 10.1152/ajpheart.00336.2010
PMCID: PMC3006278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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