Article
Beta-catenin-dependent Wnt signaling in mandibular bone regeneration.
The Journal of bone and joint surgery. American volume - 1 Feb 2008
Leucht Philipp, Kim Jae-Beom, Helms Jill A
Abstract excerpt
Osteoblasts are derived from two distinct embryonic lineages: cranial neural crest, and mesoderm. Both populations of cells are capable of forming bone and cartilage during fetal development and during adult bone repair, but whether they use equivalent molecular pathways to achieve osteoblast differentiation is unknown. We addressed this question in the context of cranial repair and focused on the role of Wnt...
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