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Article

In vitro whole-genome analysis identifies a susceptibility locus for HIV-1.

PLoS biology - 1 Feb 2008

Loeuillet Corinne, Deutsch Samuel, Ciuffi Angela, Robyr Daniel, Taffé Patrick, Muñoz Miguel, Beckmann Jacques S, Antonarakis Stylianos E, Telenti Amalio

Abstract excerpt

Advances in large-scale analysis of human genomic variability provide unprecedented opportunities to study the genetic basis of susceptibility to infectious agents. We report here the use of an in vitro system for the identification of a locus on HSA8q24.3 associated with cellular susceptibility to HIV-1. This locus was mapped through quantitative linkage analysis using cell lines from multigeneration families,...

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PMID: 18288889
DOI: 10.1371/journal.pbio.0060032
PMCID: PMC2245987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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