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Article

New splice variants of VEGF as relevant targets for the treatment of renal cell carcinoma

2022-11-07

Abstract excerpt

<title>Abstract</title> <p> Background The efficacy of anti-VEGF/VEGF receptors in the treatment of metastatic clear cell renal cell carcinoma (ccRCC) varies from patient to patient. Discovering the reasons for this variability could lead to the identification of relevant therapeutic targets. We have investigated the possibility of splicing events leading to new forms of VEGF that are less efficiently inhibited...

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Literature Corpus work
30ba5f87-0fb7-55ee-88da-d89a3d2c805d
DOI
10.21203/rs.3.rs-1684822/v2
Open publication

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New splice variants of VEGF as relevant targets for the treatment of renal cell carcinomaDOI 10.21203/rs.3.rs-1684822/v2
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