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Article

Activated Notch1 maintains the phenotype of radial glial cells and promotes their adhesion to laminin by upregulating nidogen.

Glia - 15 Apr 2008

Li Hedong, Chang Yu-Wen, Mohan Kriti, Su Hui-Wen, Ricupero Christopher L, Baridi Ajoeb, Hart Ronald P, Grumet Martin

Abstract excerpt

Radial glia are neural stem cells that exist only transiently during central nervous system (CNS) development, where they serve as scaffolds for neuronal migration. Their instability makes them difficult to study, and therefore we have isolated stabilized radial glial clones from E14.5 cortical progenitors (e.g., L2.3) after expression of v-myc. Activated Notch1 intracellular region (actNotch1) promotes radial...

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Identifiers

PMID: 18286610
DOI: 10.1002/glia.20643
PMCID: PMC2712347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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