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Article

Parthenogenetic activation of bovine oocytes using bovine and murine phospholipase C zeta

19 Feb 2008

Abstract excerpt

BACKGROUND: During natural fertilization, sperm fusion with the oocyte induces long lasting intracellular calcium oscillations which in turn are responsible for oocyte activation. PLCZ1 has been identified as the factor that the sperm delivers into the egg to induce such a response. We tested the hypothesis that PLCZ1 cRNA injection can be used to activate bovine oocytes. RESULTS: Mouse and bovine PLCZ1 cRNAs...

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PMID: 18284699
DOI: 10.1186/1471-213x-8-16

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