Article
Inflammation-related genes and the risk of Parkinson's disease: a multilocus approach.
European journal of neurology - 1 Apr 2008
Infante J, García-Gorostiaga I, Sánchez-Juan P, Sánchez-Quintana C, Gurpegui J L, Rodríguez-Rodríguez E, Mateo I, Berciano J, Combarros O
Abstract excerpt
For the first time, the multilocus approach by the set-association method has been applied for the analysis of a cluster of five genes [tumor necrosis factor alpha (TNF-alpha), interleukin 6 (IL-6), IL-8, IL-1alpha and IL-10] involved in the brain neuroinflammatory pathway in Parkinson's disease (PD), in a well-defined group of 197 PD patients and 173 control subjects from Spain. Set-association analysis did not...
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